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1

Genomic instability and cancer

Thea D. Tlsty, Amy Briot, Antonio Gualberto, Ingrid Hall, Suzanne Hess, Mary Hixon, Dhan Kuppuswamy, Serge Romanov, Marijke Sage, Alicia White

Journal:

Mutation Research/DNA Repair

Year:

1995

Language:

english

File:

PDF, 715 KB

english, 1995

2

TUMOR STROMA AND REGULATION OF CANCER DEVELOPMENT

Tlsty, Thea D., Coussens, Lisa M.

Journal:

Annual Review of Pathology Mechanisms of Disease

Year:

2006

Language:

english

File:

PDF, 960 KB

english, 2006

3

Regulatory network decoded from epigenomes of surface ectoderm-derived cell types

Lowdon, Rebecca F., Zhang, Bo, Bilenky, Misha, Mauro, Thea, Li, Daofeng, Gascard, Philippe, Sigaroudinia, Mahvash, Farnham, Peggy J., Bastian, Boris C., Tlsty, Thea D., Marra, Marco A., Hirst, Martin,

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 1.53 MB

english, 2014

4

Carcinoma-associated fibroblasts: orchestrating the composition of malignancy

Gascard, Philippe, Tlsty, Thea D.

Journal:

Genes & Development

Year:

2016

Language:

english

File:

PDF, 345 KB

english, 2016

5

Identification of additional complementation groups that regulate genomic instability

Ingrid J. Hall, Dan Gioeli, Bernard E. Weissman, Thea D. Tlsty

Journal:

Genes, Chromosomes and Cancer

Year:

1997

Language:

english

File:

PDF, 107 KB

english, 1997

6

Clonal variation of tumorigenic potential in v-Ha-ras-transformed human bronchial epithelial cells: Relationship to ras oncogene expression and CAD gene amplification

Kathleen Forrester, Jennifer Kispert, Janet H. Sanchez, Brenda I. Gerwin, Thea D. Tlsty, Curtis C. Harris

Journal:

Molecular Carcinogenesis

Year:

1994

Language:

english

File:

PDF, 1.18 MB

english, 1994

7

Extended abstract: Abrogation of cell cycle checkpoint control in preneoplastic cells

Journal:

Radiation Oncology Investigations

Year:

1995

Language:

english

File:

PDF, 237 KB

english, 1995

8

Cell cycle control and genomic instability

Journal:

Cancer and Metastasis Reviews

Year:

1995

Language:

english

File:

PDF, 118 KB

english, 1995

9

10.1038/35054579

Romanov, Serguei R., Kozakiewicz, B. Krystyna, Holst, Charles R., Stampfer, Martha R., Haupt, Larisa M., Tlsty, Thea D.

Journal:

Year:

2001

Language:

english

File:

PDF, 340 KB

english, 2001

10

Cancer: Whispering sweet somethings

Journal:

Year:

2008

Language:

english

File:

PDF, 122 KB

english, 2008

11

10.1038/4998

Journal:

Nature Genetics

Year:

1999

Language:

english

File:

PDF, 222 KB

english, 1999

12

10.1038/5056

Jiang, Xu-Rong, Jimenez, Gretchen, Chang, Edwin, Frolkis, Maria, Kusler, Brenda, Sage, Marijke, Beeche, Michelle, Bodnar, Andrea G., Wahl, Geoffrey M., Tlsty, Thea D., Chiu, Choy-Pik

Journal:

Nature Genetics

Year:

1999

Language:

english

File:

PDF, 192 KB

english, 1999

13

Luminal cells GATA have it

Journal:

Nature Cell Biology

Year:

2007

Language:

english

File:

PDF, 139 KB

english, 2007

14

An analogy between the evolution of drug resistance in bacterial communities and malignant tissues

Lambert, Guillaume, Estévez-Salmeron, Luis, Oh, Steve, Liao, David, Emerson, Beverly M., Tlsty, Thea D., Austin, Robert H.

Journal:

Nature Reviews Cancer

Year:

2011

Language:

english

File:

PDF, 916 KB

english, 2011

15

Human mammary epithelial cells exhibit a differential p53-mediated response following exposure to ionizing radiation or UV light

Meyer, Karen M, Hess, Suzanne M, Tlsty, Thea D, Leadon, Steven A

Journal:

Year:

1999

Language:

english

File:

PDF, 1.30 MB

english, 1999

16

Loss of Chromosomal Integrity in Human Mammary Epithelial Cells Subsequent to Escape from Senescence

Thea D. Tlsty, Serguei R. Romanov, B. Krystyna Kozakiewicz, Charles R. Holst, Larisa M. Haupt, Yongping G. Crawford

Journal:

Journal of Mammary Gland Biology and Neoplasia

Year:

2001

Language:

english

File:

PDF, 346 KB

english, 2001

17

Genetic and Epigenetic Changes in Mammary Epithelial Cells May Mimic Early Events in Carcinogenesis

Thea D. Tlsty, Yongping G. Crawford, Charles R. Holst, Colleen A. Fordyce, Jianmin Zhang, Kimberly McDermott, Krystyna Kozakiewicz, Mona L. Gauthier

Journal:

Journal of Mammary Gland Biology and Neoplasia

Year:

2004

Language:

english

File:

PDF, 543 KB

english, 2004

18

Tumor microenvironment and progression

Harold F. Dvorak, Valerie M. Weaver, Thea D. Tlsty, Gabriele Bergers

Journal:

Journal of Surgical Oncology

Year:

2011

Language:

english

File:

PDF, 454 KB

english, 2011

19

Stromal cells can contribute oncogenic signals

Journal:

Seminars in Cancer Biology

Year:

2001

Language:

english

File:

PDF, 1.49 MB

english, 2001

20

Abrogation of cell cycle checkpoint control in preneoplastic cells

Journal:

Cancer Genetics and Cytogenetics

Year:

1995

Language:

english

File:

PDF, 113 KB

english, 1995

21

Abrogated Response to Cellular Stress Identifies DCIS Associated with Subsequent Tumor Events and Defines Basal-like Breast Tumors

Mona L. Gauthier, Hal K. Berman, Caroline Miller, Krystyna Kozakeiwicz, Karen Chew, Dan Moore, Joseph Rabban, Yunn Yi Chen, Karla Kerlikowske, Thea D. Tlsty

Journal:

Year:

2007

Language:

english

File:

PDF, 1.68 MB

english, 2007

22

Reflections on miR-ing Effects in Metastasis

Nancy Dumont, Thea D. Tlsty

Journal:

Year:

2009

Language:

english

File:

PDF, 159 KB

english, 2009

23

Tissue States Provide Novel Insights into Attributes that Drive Metastasis

Journal:

Year:

2011

Language:

english

File:

PDF, 58 KB

english, 2011

24

Primary Cilia Regulate Branching Morphogenesis during Mammary Gland Development

Kimberly M. McDermott, Bob Y. Liu, Thea D. Tlsty, Gregory J. Pazour

Journal:

Current Biology

Year:

2010

Language:

english

File:

PDF, 1.26 MB

english, 2010

25

Functions of p53 suppress critical consequences of damage and repair in the initiation of cancer

Journal:

Year:

2002

Language:

english

File:

PDF, 147 KB

english, 2002

26

Histologically normal human mammary epithelia with silenced p16INK4a overexpress COX-2, promoting a premalignant program

Yongping G Crawford, Mona L Gauthier, Anita Joubel, Kristin Mantei, Krystyna Kozakiewicz, Cynthia A Afshari, Thea D Tlsty

Journal:

Year:

2004

Language:

english

File:

PDF, 536 KB

english, 2004

27

Induction of Tubulogenesis in Telomerase-Immortalized Human Microvascular Endothelial Cells by Glioblastoma Cells

Eleni Venetsanakos, Amer Mirza, Christie Fanton, Serguei R. Romanov, Thea Tlsty, Martin McMahon

Journal:

Experimental Cell Research

Year:

2002

Language:

english

File:

PDF, 553 KB

english, 2002

28

Replication of the dihydrofolate reductase genes on double minute chromosomes in a murine cell line

Thea D. Tlsty, Paula Adams

Journal:

Experimental Cell Research

Year:

1990

Language:

english

File:

PDF, 720 KB

english, 1990

29

A Twist of Cell Fate

Journal:

Year:

2011

Language:

english

File:

PDF, 62 KB

english, 2011

30

Cell-adhesion-dependent influences on genomic instability and carcinogenesis

Journal:

Current Opinion in Cell Biology

Year:

1998

Language:

english

File:

PDF, 606 KB

english, 1998

31

Know thy neighbor: stromal cells can contribute oncogenic signals

Thea D Tlsty, Patrick W Hein

Journal:

Current Opinion in Genetics & Development

Year:

2001

Language:

english

File:

PDF, 93 KB

english, 2001

32

Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes

Colleen A Fordyce, Kelley T Patten, Tim B Fessenden, RosaAnna DeFilippis, E Shelley Hwang, Jianxin Zhao, Thea D Tlsty

Journal:

Breast Cancer Research

Year:

2012

Language:

english

File:

PDF, 1021 KB

english, 2012

33

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

Laura R. Livingstone, Alicia White, Jason Sprouse, Elizabeth Livanos, Tyler Jacks, Thea D. Tlsty

Journal:

Year:

1992

Language:

english

File:

PDF, 6.77 MB

english, 1992

34

Genetic regulation of genomic fluidity in normal and neoplastic cells

Marijke Sage, Thea D. Tlsty

Journal:

Cancer Genetics and Cytogenetics

Year:

1993

Language:

english

File:

PDF, 100 KB

english, 1993

35

Genetic regulation of genomic fluidity in normal and neoplastic cells

Journal:

Cancer Genetics and Cytogenetics

Year:

1993

Language:

english

File:

PDF, 77 KB

english, 1993

36

52 Early epigenetic and genetic events in breast carcinogenesis

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 46 KB

english, 2010

37

Coordinate Transcriptional and Translational Repression of p53 by TGF-β1 Impairs the Stress Response

López-Díaz, Fernando J., Gascard, Philippe, Balakrishnan, Sri Kripa, Zhao, Jianxin, del Rincon, Sonia V., Spruck, Charles, Tlsty, Thea D., Emerson, Beverly M.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.67 MB

english, 2013

38

DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape

Xie, Mingchao, Hong, Chibo, Zhang, Bo, Lowdon, Rebecca F, Xing, Xiaoyun, Li, Daofeng, Zhou, Xin, Lee, Hyung Joo, Maire, Cecile L, Ligon, Keith L, Gascard, Philippe, Sigaroudinia, Mahvash, Tlsty, Thea

Journal:

Nature Genetics

Year:

2013

Language:

english

File:

PDF, 1.33 MB

english, 2013

39

Cooperation between extracellular signaling and intracellular Ras activation leads to immortalization and epithelial-to-mesenchymal transition of variant human mammary epithelial cells

N Dumont, YG Crawford, P Reynolds, TD Tlsty

Journal:

Breast Cancer Research

Year:

2005

Language:

english

File:

PDF, 1.30 MB

english, 2005

40

Genetic and epigenetic changes in early carcinogenesis

Journal:

Breast Cancer Research

Year:

2005

Language:

english

File:

PDF, 1.30 MB

english, 2005

41

Cell motility and drug gradients in the emergence of resistance to chemotherapy

Wu, A., Loutherback, K., Lambert, G., Estevez-Salmeron, L., Tlsty, T. D., Austin, R. H., Sturm, J. C.

Journal:

Proceedings of the National Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 1.06 MB

english, 2013

42

Breast Fibroblasts Modulate Early Dissemination, Tumorigenesis, and Metastasis through Alteration of Extracellular Matrix Characteristics

Dumont, Nancy, Liu, Bob, DeFilippis, Rosa Anna, Chang, Hang, Rabban, Joseph T., Karnezis, Anthony N., Tjoe, Judy A., Marx, James, Parvin, Bahram, Tlsty, Thea D.

Journal:

Year:

2013

Language:

english

File:

PDF, 4.45 MB

english, 2013

43

Gene amplification in the lac region of E. coli

Tlsty, Thea D., Albertini, Alessandra M., Miller, Jeffrey H.

Journal:

Year:

1984

Language:

english

File:

PDF, 6.05 MB

english, 1984

44

Differences in the Rates of Gene Amplification in Nontumorigenic and Tumorigenic Cell Lines as Measured by Luria-Delbruck Fluctuation Analysis

Thea D. Tlsty, Barry H. Margolin and Karen Lum

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1.10 MB

english, 1989

45

An Oncogenic Form of p53 Confers a Dominant, Gain-of-Function Phenotype that Disrupts Spindle Checkpoint Control

Antonio Gualberto, Kenneth Aldape, Krystyna Kozakiewicz and Thea D. Tlsty

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.65 MB

english, 1998

46

Game theory in the death galaxy: interaction of cancer and stromal cells in tumour microenvironment

Wu, A., Liao, D., Tlsty, T. D., Sturm, J. C., Austin, R. H.

Journal:

Interface Focus

Year:

2014

Language:

english

File:

PDF, 484 KB

english, 2014

47

Evolutionary game theory for physical and biological scientists. II. Population dynamics equations can be associated with interpretations

Liao, D., Tlsty, T. D.

Journal:

Interface Focus

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

48

Evolutionary game theory for physical and biological scientists. I. Training and validating population dynamics equations

Liao, D., Tlsty, T. D.

Journal:

Interface Focus

Year:

2014

Language:

english

File:

PDF, 1006 KB

english, 2014

49

Distribution of ultraviolet-induced DNA repair synthesis in nuclease sensitive and resistant regions of human chromatin

Smerdon, Michael J., Tlsty, Thea D., Lieberman, Michael W.

Journal:

Year:

1978

Language:

english

File:

PDF, 1.85 MB

english, 1978

50

[IEEE 2008 5th IEEE International Symposium on Biomedical Imaging (ISBI 2008) - Paris, France (2008.05.14-2008.05.17)] 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Scoring histological sections through immunohistochemistry

Hang Chang,, DeFilippis, Rosa Anna, Tlsty, Thea D., Parvin, Bahrain

Year:

2008

Language:

english

File:

PDF, 908 KB

english, 2008